Effect of withholding early parenteral nutrition in PICU on ketogenesis as potential mediator of its outcome benefit

BACKGROUND: In critically ill children, omitting early use of parenteral nutrition (late-PN versus early-PN) reduced infections, accelerated weaning from mechanical ventilation, and shortened PICU stay. We hypothesized that fasting-induced ketogenesis mediates these benefits. METHODS: In a secondary...

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Publicat a:Crit Care
Autors principals: De Bruyn, Astrid, Gunst, Jan, Goossens, Chloë, Vander Perre, Sarah, Guerra, Gonzalo G., Verbruggen, Sascha, Joosten, Koen, Langouche, Lies, Van den Berghe, Greet
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7456767/
https://ncbi.nlm.nih.gov/pubmed/32867803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-020-03256-z
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