Robust T Cell Response Toward Spike, Membrane, and Nucleocapsid SARS-CoV-2 Proteins Is Not Associated with Recovery in Critical COVID-19 Patients

T cell immunity toward SARS-CoV-2 spike (S-), membrane (M-), and nucleocapsid (N-) proteins may define COVID-19 severity. Therefore, we compare the SARS-CoV-2-reactive T cell responses in moderate, severe, and critical COVID-19 patients and unexposed donors. Overlapping peptide pools of all three pr...

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Библиографические подробности
Опубликовано в: :Cell Rep Med
Главные авторы: Thieme, Constantin J., Anft, Moritz, Paniskaki, Krystallenia, Blazquez-Navarro, Arturo, Doevelaar, Adrian, Seibert, Felix S., Hoelzer, Bodo, Konik, Margarethe Justine, Berger, Marc Moritz, Brenner, Thorsten, Tempfer, Clemens, Watzl, Carsten, Meister, Toni L., Pfaender, Stephanie, Steinmann, Eike, Dolff, Sebastian, Dittmer, Ulf, Westhoff, Timm H., Witzke, Oliver, Stervbo, Ulrik, Roch, Toralf, Babel, Nina
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7456276/
https://ncbi.nlm.nih.gov/pubmed/32904468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xcrm.2020.100092
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