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Glucocorticoid Resistance in Premature Adrenarche and PCOS: From Childhood to Adulthood

CONTEXT: We hypothesize that impaired glucocorticoid sensitivity (GC sensitivity) plays a role in the development of premature adrenarche (PA) and polycystic ovarian syndrome (PCOS) by increasing androgen synthesis. OBJECTIVE: To study glucocorticoid sensitivity in vitro in subjects with PA and PCOS...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: Panayiotopoulos, Aristotle, Bhangoo, Amrit, Khurana, Divya, Ten, Svetlana, Michl, Josef, Ghanny, Steven
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7456159/
https://ncbi.nlm.nih.gov/pubmed/32904537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa111
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