HIF-1α overexpression in mesenchymal stem cell-derived exosomes mediates cardioprotection in myocardial infarction by enhanced angiogenesis

BACKGROUND: Myocardial infarction (MI) is a severe disease that often associated with dysfunction of angiogenesis. Cell-based therapies for MI using mesenchymal stem cell (MSC)-derived exosomes have been well studied due to their strong proangiogenic effect. Genetic modification is one of the most c...

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Bibliographic Details
Published in:Stem Cell Res Ther
Main Authors: Sun, Jiacheng, Shen, Han, Shao, Lianbo, Teng, Xiaomei, Chen, Yueqiu, Liu, Xuan, Yang, Ziying, Shen, Zhenya
Format: Artigo
Language:Inglês
Published: BioMed Central 2020
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7455909/
https://ncbi.nlm.nih.gov/pubmed/32859268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01881-7
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