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LIMK2 promotes the metastatic progression of triple-negative breast cancer by activating SRPK1

Triple-negative breast cancer (TNBC) is a highly metastatic breast cancer subtype and due to the lack of hormone receptors and HER2 expression, TNBC has limited therapeutic options with chemotherapy being the primary choice for systemic therapy. LIM Domain Kinase 2 (LIMK2) is a serine/threonine kina...

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Detalhes bibliográficos
Publicado no:Oncogenesis
Main Authors: Malvi, Parmanand, Janostiak, Radoslav, Chava, Suresh, Manrai, Padmini, Yoon, Esther, Singh, Kamaljeet, Harigopal, Malini, Gupta, Romi, Wajapeyee, Narendra
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7455732/
https://ncbi.nlm.nih.gov/pubmed/32859889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-020-00263-1
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