Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9 Å

Gap junctions establish direct pathways for cells to transfer metabolic and electrical messages. The local lipid environment is known to affect the structure, stability and intercellular channel activity of gap junctions; however, the molecular basis for these effects remains unknown. Here, we incor...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Flores, Jonathan A., Haddad, Bassam G., Dolan, Kimberly A., Myers, Janette B., Yoshioka, Craig C., Copperman, Jeremy, Zuckerman, Daniel M., Reichow, Steve L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7455559/
https://ncbi.nlm.nih.gov/pubmed/32859914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18120-5
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