Genetic overlap and causal inferences between kidney function and cerebrovascular disease

OBJECTIVE: Leveraging large-scale genetic data, we aimed to identify shared pathogenic mechanisms and causal relationships between impaired kidney function and cerebrovascular disease phenotypes. METHODS: We used summary statistics from genome-wide association studies (GWAS) of kidney function trait...

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Pubblicato in:Neurology
Autori principali: Marini, Sandro, Georgakis, Marios K., Chung, Jaeyoon, Henry, Jonathan Q.A., Dichgans, Martin, Rosand, Jonathan, Malik, Rainer, Anderson, Christopher D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Lippincott Williams & Wilkins 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7455337/
https://ncbi.nlm.nih.gov/pubmed/32439819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000009642
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