Genetically determined blood pressure, antihypertensive drug classes, and risk of stroke subtypes

OBJECTIVE: We employed Mendelian randomization to explore whether the effects of blood pressure (BP) and BP-lowering through different antihypertensive drug classes on stroke risk vary by stroke etiology. METHODS: We selected genetic variants associated with systolic and diastolic BP and BP-lowering...

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Pubblicato in:Neurology
Autori principali: Georgakis, Marios K., Gill, Dipender, Webb, Alastair J.S., Evangelou, Evangelos, Elliott, Paul, Sudlow, Cathie L.M., Dehghan, Abbas, Malik, Rainer, Tzoulaki, Ioanna, Dichgans, Martin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Lippincott Williams & Wilkins 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7455321/
https://ncbi.nlm.nih.gov/pubmed/32611631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000009814
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