Viruses harness YxxØ motif to interact with host AP2M1 for replication: A vulnerable broad-spectrum antiviral target

Targeting a universal host protein exploited by most viruses would be a game-changing strategy that offers broad-spectrum solution and rapid pandemic control including the current COVID-19. Here, we found a common YxxØ-motif of multiple viruses that exploits host AP2M1 for intracellular trafficking....

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מידע ביבליוגרפי
הוצא לאור ב:Sci Adv
Main Authors: Yuan, Shuofeng, Chu, Hin, Huang, Jingjing, Zhao, Xiaoyu, Ye, Zi-Wei, Lai, Pok-Man, Wen, Lei, Cai, Jian-Piao, Mo, Yufei, Cao, Jianli, Liang, Ronghui, Poon, Vincent Kwok-Man, Sze, Kong-Hung, Zhou, Jie, To, Kelvin Kai-Wang, Chen, Zhiwei, Chen, Honglin, Jin, Dong-Yan, Chan, Jasper Fuk-Woo, Yuen, Kwok-Yung
פורמט: Artigo
שפה:Inglês
יצא לאור: American Association for the Advancement of Science 2020
נושאים:
Research Articles
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7455044/
https://ncbi.nlm.nih.gov/pubmed/32923629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aba7910
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