COVID-19 infection alters kynurenine and fatty acid metabolism, correlating with IL-6 levels and renal status

BACKGROUND: Reprogramming of host metabolism supports viral pathogenesis by fueling viral proliferation, by providing, for example, free amino acids and fatty acids as building blocks. METHODS: To investigate metabolic effects of SARS-CoV-2 infection, we evaluated serum metabolites of patients with...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Thomas, Tiffany, Stefanoni, Davide, Reisz, Julie A., Nemkov, Travis, Bertolone, Lorenzo, Francis, Richard O., Hudson, Krystalyn E., Zimring, James C., Hansen, Kirk C., Hod, Eldad A., Spitalnik, Steven L., D’Alessandro, Angelo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Clinical Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7453907/
https://ncbi.nlm.nih.gov/pubmed/32559180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.140327
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