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CD19-targeted CAR regulatory T cells suppress B cell pathology without GvHD

Regulatory T cells (Tregs) play essential roles in maintaining immunological self-tolerance and preventing autoimmunity. The adoptive transfer of antigen-specific Tregs has been expected to be a potent therapeutic method for autoimmune diseases, severe allergy, and rejection in organ transplantation...

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Bibliografske podrobnosti
izdano v:JCI Insight
Main Authors: Imura, Yuki, Ando, Makoto, Kondo, Taisuke, Ito, Minako, Yoshimura, Akihiko
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7453900/
https://ncbi.nlm.nih.gov/pubmed/32525846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.136185
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