Short-term metreleptin treatment of patients with anorexia nervosa: rapid on-set of beneficial cognitive, emotional, and behavioral effects

To examine the hypothesis that normalization of low circulating leptin levels in patients with anorexia nervosa ameliorates hyperactivity, three seriously ill females with hyperactivity were treated off-label with metreleptin (recombinant human leptin) for up to 14 days. Drive for activity, repetiti...

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Veröffentlicht in:Transl Psychiatry
Hauptverfasser: Milos, Gabriella, Antel, Jochen, Kaufmann, Lisa-Katrin, Barth, Nikolaus, Koller, Antonia, Tan, Susanne, Wiesing, Urban, Hinney, Anke, Libuda, Lars, Wabitsch, Martin, von Känel, Roland, Hebebrand, Johannes
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7453199/
https://ncbi.nlm.nih.gov/pubmed/32855384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-020-00977-1
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