Comparative Population Pharmacokinetics of Darunavir in SARS-CoV-2 Patients vs. HIV Patients: The Role of Interleukin-6

BACKGROUND: Darunavir is an anti-HIV protease inhibitor repurposed for SARS-CoV-2 treatment. OBJECTIVE: The aim of this study was to assess the population pharmacokinetics of darunavir in SARS-CoV-2 patients compared with HIV patients. METHODS: Two separate models were created by means of a nonlinea...

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Vydáno v:Clin Pharmacokinet
Hlavní autoři: Cojutti, Pier Giorgio, Londero, Angela, Della Siega, Paola, Givone, Filippo, Fabris, Martina, Biasizzo, Jessica, Tascini, Carlo, Pea, Federico
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2020
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Original Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7453069/
https://ncbi.nlm.nih.gov/pubmed/32856282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-020-00933-8
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