Systemic Treatment With Nicotinamide Riboside Is Protective in a Mouse Model of Light-Induced Retinal Degeneration

PURPOSE: Maintaining levels of nicotinamide adenine dinucleotide (NAD(+)), a coenzyme critical for cellular energetics and biosynthetic pathways, may be therapeutic in retinal disease because retinal NAD(+) levels decline during retinal damage and degeneration. The purpose of this study was to inves...

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Bibliografske podrobnosti
izdano v:Invest Ophthalmol Vis Sci
Main Authors: Zhang, Xian, Henneman, Nathaniel F., Girardot, Preston E., Sellers, Jana T., Chrenek, Micah A., Li, Ying, Wang, Jiaxing, Brenner, Charles, Nickerson, John M., Boatright, Jeffrey H.
Format: Artigo
Jezik:Inglês
Izdano: The Association for Research in Vision and Ophthalmology 2020
Teme:
Biochemistry and Molecular Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7452859/
https://ncbi.nlm.nih.gov/pubmed/32852543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.61.10.47
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