Hypermethylation status of DAPK, MGMT and RUNX3 in HPV negative oral and oropharyngeal squamous cell carcinoma

Squamous cell carcinoma of the oral cavity and oropharynx is the sixth most common type of cancer in the world. During tumorigenesis, gene promoter hypermethylation is considered an important mechanism of transcription silencing of tumor suppressor genes, such as DAPK, MGMT and RUNX3. These genes pa...

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Bibliografski detalji
Izdano u:Genet Mol Biol
Glavni autori: dos Reis, Raquel Silva, dos Santos, Jéssica Aflávio, de Abreu, Priscila Marinho, Dettogni, Raquel Spinassé, dos Santos, Eldamária de Vargas Wolfgramm, Stur, Elaine, Agostini, Lidiane Pignaton, Anders, Quézia Silva, Alves, Lyvia Neves Rebello, do Valle, Isabella Bittencourt, Lima, Marília Arantes, Souza, Evandro Duccini, de Podestá, José Roberto Vasconcelos, von Zeidler, Sandra Ventorin, Cordeiro-Silva, Melissa de Freitas, Louro, Iúri Drumond
Format: Artigo
Jezik:Inglês
Izdano: Sociedade Brasileira de Genética 2020
Teme:
Human and Medical Genetics
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7452731/
https://ncbi.nlm.nih.gov/pubmed/32870234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1678-4685-GMB-2019-0334
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