Optogenetic Stimulation of Vagal Efferent Activity Preserves Left Ventricular Function in Experimental Heart Failure

Large clinical trials designed to test the efficacy of vagus nerve stimulation (VNS) in patients with heart failure did not demonstrate benefits with respect to the primary endpoints. The nonselective nature of VNS may account for the failure to translate promising results of preclinical and earlier...

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Bibliografiske detaljer
Udgivet i:JACC Basic Transl Sci
Main Authors: Machhada, Asif, Hosford, Patrick S., Dyson, Alex, Ackland, Gareth L., Mastitskaya, Svetlana, Gourine, Alexander V.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
Fag:
PRECLINICAL RESEARCH
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7452237/
https://ncbi.nlm.nih.gov/pubmed/32875170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2020.06.002
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