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Model-driven analysis of mutant fitness experiments improves genome-scale metabolic models of Zymomonas mobilis ZM4

Genome-scale metabolic models have been utilized extensively in the study and engineering of the organisms they describe. Here we present the analysis of a published dataset from pooled transposon mutant fitness experiments as an approach for improving the accuracy and gene-reaction associations of...

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Publicat a:PLoS Comput Biol
Autors principals: Ong, Wai Kit, Courtney, Dylan K., Pan, Shu, Andrade, Ramon Bonela, Kiley, Patricia J., Pfleger, Brian F., Reed, Jennifer L.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7451989/
https://ncbi.nlm.nih.gov/pubmed/32804944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008137
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