Epistatic interactions between killer immunoglobulin-like receptors and human leukocyte antigen ligands are associated with ankylosing spondylitis

The killer immunoglobulin-like receptors (KIRs), found predominantly on the surface of natural killer (NK) cells and some T-cells, are a collection of highly polymorphic activating and inhibitory receptors with variable specificity for class I human leukocyte antigen (HLA) ligands. Fifteen KIR genes...

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發表在:PLoS Genet
Main Authors: Hanson, Aimee L., Vukcevic, Damjan, Leslie, Stephen, Harris, Jessica, Lê Cao, Kim-Anh, Kenna, Tony J., Brown, Matthew A.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2020
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7451988/
https://ncbi.nlm.nih.gov/pubmed/32804949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008906
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