Inhibition of circulating dipeptidyl-peptidase 3 restores cardiac function in a sepsis-induced model in rats: A proof of concept study

Sepsis is a global economic and health burden. Dipeptidyl peptidase 3 (DPP3) is elevated in the plasma of septic patients. The highest levels of circulating DPP3 (cDPP3) are found in non-survivor septic shock patients. The aim of this study was to evaluate the benefits of inhibiting cDPP3 by a speci...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Deniau, Benjamin, Blet, Alice, Santos, Karine, Vaittinada Ayar, Prabakar, Genest, Magali, Kästorf, Mandy, Sadoune, Malha, de Sousa Jorge, Andreia, Samuel, Jane Lise, Vodovar, Nicolas, Bergmann, Andreas, Mebazaa, Alexandre, Azibani, Feriel
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2020
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7451654/
https://ncbi.nlm.nih.gov/pubmed/32853284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0238039
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