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Wolfram Syndrome: a Monogenic Model to Study Diabetes Mellitus and Neurodegeneration

Wolfram syndrome (WS) is a rare, progressive disorder characterized by childhood-onset diabetes mellitus, optic nerve atrophy, hearing loss, diabetes insipidus, and neurodegeneration. Currently, there is no effective treatment for WS, and patients typically die between 30 and 40 years of age. WS is...

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Bibliografske podrobnosti
izdano v:Curr Opin Physiol
Main Authors: Fischer, Tom T., Ehrlich, Barbara E.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7451204/
https://ncbi.nlm.nih.gov/pubmed/32864536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cophys.2020.07.009
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