Acoustic Trauma Causes Cochlear Pericyte-to-Myofibroblast–Like Cell Transformation and Vascular Degeneration, and Transplantation of New Pericytes Prevents Vascular Atrophy

Acoustic trauma disrupts cochlear blood flow and damages sensory hair cells. Damage and regression of capillaries after acoustic trauma have long been observed, but the underlying mechanism of pathology has not been understood. We show herein that loud sound causes change of phenotype from neural/gl...

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Détails bibliographiques
Publié dans:Am J Pathol
Auteurs principaux: Hou, Zhiqiang, Neng, Lingling, Zhang, Jinhui, Cai, Jing, Wang, Xiaohan, Zhang, Yunpei, Lopez, Ivan A., Shi, Xiaorui
Format: Artigo
Langue:Inglês
Publié: American Society for Investigative Pathology 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7450261/
https://ncbi.nlm.nih.gov/pubmed/32562655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2020.05.019
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