Pharmacological depletion of microglia and perivascular macrophages prevents Vascular Cognitive Impairment in Ang II-induced hypertension

Rationale: Hypertension is a major risk factor for cerebral small vessel disease, the most prevalent cause of vascular cognitive impairment. As we have shown, hypertension induced by a prolonged Angiotensin II infusion is associated with increased permeability of the blood-brain barrier (BBB), chron...

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Udgivet i:Theranostics
Main Authors: Kerkhofs, Danielle, van Hagen, Britt T., Milanova, Irina V., Schell, Kimberly J., van Essen, Helma, Wijnands, Erwin, Goossens, Pieter, Blankesteijn, W. Matthijs, Unger, Thomas, Prickaerts, Jos, Biessen, Erik A., van Oostenbrugge, Robert J., Foulquier, Sébastien
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2020
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449902/
https://ncbi.nlm.nih.gov/pubmed/32863942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.44394
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