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Application of a Biologically Contained Reporter System To Study Gain-of-Function H5N1 Influenza A Viruses with Pandemic Potential

Natural adaptation of an antigenically novel avian influenza A virus (IAV) to be transmitted efficiently in humans has the potential to trigger a devastating pandemic. Understanding viral genetic determinants underlying adaptation is therefore critical for pandemic preparedness, as the knowledge gai...

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Publicat a:mSphere
Autors principals: Spieler, Eva E., Moritz, Eva, Stertz, Silke, Hale, Benjamin G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449622/
https://ncbi.nlm.nih.gov/pubmed/32848003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00423-20
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