Computational Chemogenomics Drug Repositioning Strategy Enables the Discovery of Epirubicin as a New Repurposed Hit for Plasmodium falciparum and P. vivax

Widespread resistance against antimalarial drugs thwarts current efforts for controlling the disease and urges the discovery of new effective treatments. Drug repositioning is increasingly becoming an attractive strategy since it can reduce costs, risks, and time-to-market. Herein, we have used this...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Ferreira, Letícia Tiburcio, Rodrigues, Juliana, Cassiano, Gustavo Capatti, Tavella, Tatyana Almeida, Tomaz, Kaira Cristina Peralis, Baia-da-Silva, Djane Clarys, Souza, Macejane Ferreira, Lima, Marilia Nunes do Nascimento, Mottin, Melina, Almeida, Ludimila Dias, Calit, Juliana, Puça, Maria Carolina Silva de Barros, Melo, Gisely Cardoso, Bargieri, Daniel Youssef, Lopes, Stefanie Costa Pinto, Lacerda, Marcus Vinicius Guimarães, Bilsland, Elizabeth, Sunnerhagen, Per, Neves, Bruno Junior, Andrade, Carolina Horta, Cravo, Pedro Vitor Lemos, Costa, Fabio Trindade Maranhão
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449180/
https://ncbi.nlm.nih.gov/pubmed/32601162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02041-19
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