Computational Chemogenomics Drug Repositioning Strategy Enables the Discovery of Epirubicin as a New Repurposed Hit for Plasmodium falciparum and P. vivax

Widespread resistance against antimalarial drugs thwarts current efforts for controlling the disease and urges the discovery of new effective treatments. Drug repositioning is increasingly becoming an attractive strategy since it can reduce costs, risks, and time-to-market. Herein, we have used this...

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Bibliografische gegevens
Gepubliceerd in:Antimicrob Agents Chemother
Hoofdauteurs: Ferreira, Letícia Tiburcio, Rodrigues, Juliana, Cassiano, Gustavo Capatti, Tavella, Tatyana Almeida, Tomaz, Kaira Cristina Peralis, Baia-da-Silva, Djane Clarys, Souza, Macejane Ferreira, Lima, Marilia Nunes do Nascimento, Mottin, Melina, Almeida, Ludimila Dias, Calit, Juliana, Puça, Maria Carolina Silva de Barros, Melo, Gisely Cardoso, Bargieri, Daniel Youssef, Lopes, Stefanie Costa Pinto, Lacerda, Marcus Vinicius Guimarães, Bilsland, Elizabeth, Sunnerhagen, Per, Neves, Bruno Junior, Andrade, Carolina Horta, Cravo, Pedro Vitor Lemos, Costa, Fabio Trindade Maranhão
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2020
Onderwerpen:
Experimental Therapeutics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449180/
https://ncbi.nlm.nih.gov/pubmed/32601162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02041-19
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