In Vivo Repair of a Protein Underlying a Neurological Disorder by Programmable RNA Editing

Programmable RNA editing is gaining momentum as an approach to repair mutations, but its efficiency in repairing endogenous mutant RNA in complex tissue is unknown. Here we apply this approach to the brain and successfully repair a guanosine-to-adenosine mutation in methyl CpG binding protein 2 RNA...

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Detaylı Bibliyografya
Yayımlandı:Cell Rep
Asıl Yazarlar: Sinnamon, John R., Kim, Susan Y., Fisk, Jenna R., Song, Zhen, Nakai, Hiroyuki, Jeng, Sophia, McWeeney, Shannon K., Mandel, Gail
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449137/
https://ncbi.nlm.nih.gov/pubmed/32668243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107878
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