Genome-wide association meta-analysis for early age-related macular degeneration highlights novel loci and insights for advanced disease

BACKGROUND: Advanced age-related macular degeneration (AMD) is a leading cause of blindness. While around half of the genetic contribution to advanced AMD has been uncovered, little is known about the genetic architecture of early AMD. METHODS: To identify genetic factors for early AMD, we conducted...

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Gepubliceerd in:BMC Med Genomics
Hoofdauteurs: Winkler, Thomas W., Grassmann, Felix, Brandl, Caroline, Kiel, Christina, Günther, Felix, Strunz, Tobias, Weidner, Lorraine, Zimmermann, Martina E., Korb, Christina A., Poplawski, Alicia, Schuster, Alexander K., Müller-Nurasyid, Martina, Peters, Annette, Rauscher, Franziska G., Elze, Tobias, Horn, Katrin, Scholz, Markus, Cañadas-Garre, Marisa, McKnight, Amy Jayne, Quinn, Nicola, Hogg, Ruth E., Küchenhoff, Helmut, Heid, Iris M., Stark, Klaus J., Weber, Bernhard H. F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2020
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449002/
https://ncbi.nlm.nih.gov/pubmed/32843070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-020-00760-7
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