Individualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT): A Bayesian Adaptive Platform Trial to Develop Precision Medicines for Patients With Glioblastoma

PURPOSE: Adequately prioritizing the numerous therapies and biomarkers available in late-stage testing for patients with glioblastoma (GBM) requires an efficient clinical testing platform. We developed and implemented INSIGhT (Individualized Screening Trial of Innovative Glioblastoma Therapy) as a n...

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Pubblicato in:JCO Precis Oncol
Autori principali: Alexander, Brian M., Trippa, Lorenzo, Gaffey, Sarah, Arrillaga-Romany, Isabel C., Lee, Eudocia Q., Rinne, Mikael L., Ahluwalia, Manmeet S., Colman, Howard, Fell, Geoffrey, Galanis, Evanthia, de Groot, John, Drappatz, Jan, Lassman, Andrew B., Meredith, David M., Nabors, L. Burt, Santagata, Sandro, Schiff, David, Welch, Mary R., Ligon, Keith L., Wen, Patrick Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Clinical Oncology 2019
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Special Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7448806/
https://ncbi.nlm.nih.gov/pubmed/32914038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/PO.18.00071
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