Escalated oxycodone self-administration causes differential striatal mRNA expression of FGFs and IEGs following abstinence-associated incubation of oxycodone craving

Addiction to prescribed opioids including oxycodone has reached tragic levels. Herein, we investigated the relevance of fibroblast growth factors (FGFs) and immediate early genes (IEGs) to withdrawal-induced incubation of drug craving following escalated oxycodone self-administration (SA). Rats were...

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Detalhes bibliográficos
Publicado no:Neuroscience
Main Authors: Blackwood, Christopher A., Leary, Michael, Salisbury, Aaron, McCoy, Michael T., Cadet, Jean Lud
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7448685/
https://ncbi.nlm.nih.gov/pubmed/31351142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2019.07.030
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