Performance of PCR/Electrospray Ionization-Mass Spectrometry on Whole Blood for Detection of Bloodstream Microorganisms in Patients with Suspected Sepsis

Blood culture (BC) often fails to detect bloodstream microorganisms in sepsis. However, molecular diagnostics hold great potential. The molecular method PCR/electrospray ionization-mass spectrometry (PCR/ESI-MS) can detect DNA from hundreds of different microorganisms in whole blood. The aim of the...

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Dettagli Bibliografici
Pubblicato in:J Clin Microbiol
Autori principali: Strålin, Kristoffer, Rothman, Richard E., Özenci, Volkan, Barkataki, Kieron, Brealey, David, Dhiman, Neelam, Poling, Lara, Kurz, Michael C., Limaye, Ajit P., LoVecchio, Frank, Lowery, Kristin, Miller, Loren G., Moran, Gregory J., Overcash, J. Scott, Parekh, Amisha, Peacock, W. Frank, Rivers, Emanuel P., Sims, Matthew, Stubbs, Amy M., Sundqvist, Martin, Ullberg, Måns, Carroll, Karen C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2020
Soggetti:
Bacteriology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7448645/
https://ncbi.nlm.nih.gov/pubmed/32641399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01860-19
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