Biological and structural characterization of murine TRALI antibody reveals increased Fc-mediated complement activation

Transfusion-related acute lung injury (TRALI) remains a leading cause of transfusion-related deaths. In most cases, anti-leukocyte antibodies in the transfusion product trigger TRALI, but not all anti-leukocyte antibodies cause TRALI. It has been shown that the anti–major histocompatibility complex...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Zeeuw van der Laan, Eveline A. N., van der Velden, Saskia, Bentlage, Arthur E. H., Larsen, Mads D., van Osch, Thijs L. J., Mok, Juk Yee, Brasser, Giso, Geerdes, Dionne M., Koeleman, Carolien A. M., Nouta, Jan, Semple, John W., Porcelijn, Leendert, van Esch, Wim J. E., Wuhrer, Manfred, van der Schoot, C. Ellen, Vidarsson, Gestur, Kapur, Rick
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Transfusion Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7448591/
https://ncbi.nlm.nih.gov/pubmed/32810222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002291
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