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KRAS as a druggable target in NSCLC: Rising like a phoenix after decades of development failures
Cancers of nearly all lineages harbor alterations that deregulate mitogen-activated protein kinase signaling, a crucial signaling pathway for tumor formation and maintenance. Of these, KRAS mutations are the most frequent gain-of-function alterations found in patients with cancer. In particular they...
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| Vydáno v: | Cancer Treat Rev |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7448574/ https://ncbi.nlm.nih.gov/pubmed/32062493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ctrv.2020.101978 |
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