A novel tumor mutational burden estimation model as a predictive and prognostic biomarker in NSCLC patients

BACKGROUND: Tumor mutational burden (TMB) has both prognostic value in resected non-small cell lung cancer (NSCLC) patients and predictive value for immunotherapy response. However, TMB evaluation by whole-exome sequencing (WES) is expensive and time-consuming, hampering its application in clinical...

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Detalhes bibliográficos
Publicado no:BMC Med
Main Authors: Tian, Yanhua, Xu, Jiachen, Chu, Qian, Duan, Jianchun, Zhang, Jianjun, Bai, Hua, Yang, Zhenlin, Fang, Wenfeng, Cai, Liangliang, Wan, Rui, Fei, Kailun, He, Jie, Gao, Shugeng, Zhang, Li, Wang, Zhijie, Wang, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7448445/
https://ncbi.nlm.nih.gov/pubmed/32843031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-020-01694-8
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