Kevetrin induces apoptosis in TP53 wild-type and mutant acute myeloid leukemia cells

Tumor protein p53 is a key regulator of several cellular pathways, including DNA repair, cell cycle and angiogenesis. Kevetrin exhibits p53-dependent as well as-independent activity in solid tumors, while its effects on leukemic cells remain unknown. The aim of the present study was to analyze the r...

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Vydáno v:Oncol Rep
Hlavní autoři: Napolitano, Roberta, De Matteis, Serena, Carloni, Silvia, Bruno, Samantha, Abbati, Giulia, Capelli, Laura, Ghetti, Martina, Bochicchio, Maria Teresa, Liverani, Chiara, Mercatali, Laura, Calistri, Daniele, Cuneo, Antonio, Menon, Krishna, Musuraca, Gerardo, Martinelli, Giovanni, Simonetti, Giorgia
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7448420/
https://ncbi.nlm.nih.gov/pubmed/32945487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2020.7730
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