In Vivo Genome and Methylome Adaptation of cag-Negative Helicobacter pylori during Experimental Human Infection

Multiple studies have demonstrated rapid bacterial genome evolution during chronic infection with Helicobacter pylori. In contrast, little was known about genetic changes during the first stages of infection, when selective pressure is likely to be highest. Using single-molecule, real-time (SMRT) an...

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Veröffentlicht in:mBio
Hauptverfasser: Estibariz, Iratxe, Ailloud, Florent, Woltemate, Sabrina, Bunk, Boyke, Spröer, Cathrin, Overmann, Jörg, Aebischer, Toni, Meyer, Thomas F., Josenhans, Christine, Suerbaum, Sebastian
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2020
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7448279/
https://ncbi.nlm.nih.gov/pubmed/32843556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01803-20
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