Heterologous Expression of the Unusual Terreazepine Biosynthetic Gene Cluster Reveals a Promising Approach for Identifying New Chemical Scaffolds

Advances in genome sequencing have revitalized natural product discovery efforts, revealing the untapped biosynthetic potential of fungi. While the volume of genomic data continues to expand, discovery efforts are slowed due to the time-consuming nature of experiments required to characterize new mo...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Caesar, Lindsay K., Robey, Matthew T., Swyers, Michael, Islam, Md N., Ye, Rosa, Vagadia, Purav P., Schiltz, Gary E., Thomas, Paul M., Wu, Chengcang C., Kelleher, Neil L., Keller, Nancy P., Bok, Jin Woo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7448278/
https://ncbi.nlm.nih.gov/pubmed/32843555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01691-20
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