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Blood substitution therapy rescues the brain of mice from ischemic damage

Acute stroke causes complex, pathological, and systemic responses that have not been treatable by any single medication. In this study, using a murine transient middle cerebral artery occlusion stroke model, a novel therapeutic strategy is proposed, where blood replacement (BR) robustly reduces infa...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Ren, Xuefang, Hu, Heng, Farooqi, Imran, Simpkins, James W.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7447645/
https://ncbi.nlm.nih.gov/pubmed/32843630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17930-x
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