Tongxinluo attenuates oxygen-glucose-serum deprivation/restoration-induced endothelial barrier breakdown via peroxisome proliferator activated receptor-α/angiopoietin-like 4 pathway in high glucose-incubated human cardiac microvascular endothelial cells

BACKGROUND: Traditional Chinese medicine Tongxinluo (TXL) has been widely used to treat coronary artery disease in China, since it could reduce myocardial infarct size and ischemia/reperfusion injury in both non-diabetic and diabetic conditions. It has been shown that TXL could regulate peroxisome p...

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Vydáno v:Medicine (Baltimore)
Hlavní autoři: Qi, Kang, Yang, Yuejin, Geng, Yongjian, Cui, Hehe, Li, Xiangdong, Jin, Chen, Chen, Guihao, Tian, Xiaqiu, Meng, Xianmin
Médium: Artigo
Jazyk:Inglês
Vydáno: Lippincott Williams & Wilkins 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7447398/
https://ncbi.nlm.nih.gov/pubmed/32846824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000021821
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