Crimean-Congo hemorrhagic fever virus strains Hoti and Afghanistan cause viremia and mild clinical disease in cynomolgus monkeys

BACKGROUND: Development of vaccines and therapies against Crimean-Congo hemorrhagic fever virus (CCHFV) have been hindered by the lack of immunocompetent animal models. Recently, a lethal nonhuman primate model based on the CCHFV Hoti strain was reported. CCHFV Hoti caused severe disease in cynomolg...

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Publicado en:PLoS Negl Trop Dis
Main Authors: Cross, Robert W., Prasad, Abhishek N., Borisevich, Viktoriya, Geisbert, Joan B., Agans, Krystle N., Deer, Daniel J., Fenton, Karla A., Geisbert, Thomas W.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2020
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7447009/
https://ncbi.nlm.nih.gov/pubmed/32790668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0008637
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