Up-regulation of Nrf2 is involved in FGF21 mediated fenofibrate protection against type 1 diabetic nephropathy

The lipid lowering medication, fenofibrate (FF), is a peroxisome proliferator-activated receptor-alpha (PPARα) agonist, possessing beneficial effects for type 2 diabetic nephropathy (DN). We investigated whether FF can prevent the development of type 1 DN, and the underlying mechanisms. Diabetes was...

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Detaylı Bibliyografya
Yayımlandı:Free Radic Biol Med
Asıl Yazarlar: Cheng, Yanli, Zhang, Jingjing, Guo, Weiying, Li, Fengsheng, Sun, Weixia, Chen, Jing, Zhang, Chi, Lu, Xuemian, Tan, Yi, Feng, Wenke, Fu, Yaowen, Liu, Gilbert C., Xu, Zhonggao, Cai, Lu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7446394/
https://ncbi.nlm.nih.gov/pubmed/26849944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2016.02.002
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