Contribution of Inherited DNA-Repair Gene Mutations to Hormone-Sensitive and Castrate-Resistant Metastatic Prostate Cancer and Implications for Clinical Outcome

PURPOSE: To compare the prevalence of germline mutations in metastatic hormone-sensitive prostate cancer (mHSPC) and metastatic castrate-resistant prostate cancer (mCRPC) and assess the impact of mutations on progression to castration resistance and overall survival. METHODS: Targeted sequencing of...

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Publicat a:JCO Precis Oncol
Autors principals: Yadav, Siddhartha, Hart, Steven N., Hu, Chunling, Hillman, David, Lee, Kun Y., Gnanaolivu, Rohan, Na, Jie, Polley, Eric C., Couch, Fergus J., Kohli, Manish
Format: Artigo
Idioma:Inglês
Publicat: American Society of Clinical Oncology 2019
Matèries:
Original Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7446380/
https://ncbi.nlm.nih.gov/pubmed/32923857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/PO.19.00067
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