Use of a Targeted Exome Next-Generation Sequencing Panel Offers Therapeutic Opportunity and Clinical Benefit in a Subset of Patients With Advanced Cancers

PURPOSE: Smaller hotspot-based next-generation sequencing (NGS) panels have emerged to support standard of care therapy for patients with cancer. When standard treatments fail, it is unknown whether additional testing using an expanded panel of genes provides any benefit. The purpose of this study w...

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Vydáno v:JCO Precis Oncol
Hlavní autoři: Kopetz, Scott, Mills Shaw, Kenna R., Lee, J. Jack, Zhang, Jiexin, Litzenburger, Beate, Holla, Vijaykumar, Kinyua, Walter, Broaddus, Emily, Daniels, Molly S., Meric-Bernstam, Funda, Broaddus, Russell R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Clinical Oncology 2019
Témata:
Original Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7446317/
https://ncbi.nlm.nih.gov/pubmed/32914008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/PO.18.00213
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