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Lower peripheral helper T cell levels in the synovium are associated with a better response to anti-TNF therapy in rheumatoid arthritis

BACKGROUND: The mechanisms by which only some rheumatoid arthritis (RA) patients respond favorably to TNF blockade are still poorly characterized. The goal of this study was to identify biological features that explain this differential response using a multilevel transcriptome analysis of the synov...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Julià, Antonio, Ávila, Gabriela, Celis, Raquel, Sanmartí, Raimon, Ramírez, Julio, Marsal, Sara, Cañete, Juan D.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7446220/
https://ncbi.nlm.nih.gov/pubmed/32843099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-020-02287-9
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