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Lower peripheral helper T cell levels in the synovium are associated with a better response to anti-TNF therapy in rheumatoid arthritis

BACKGROUND: The mechanisms by which only some rheumatoid arthritis (RA) patients respond favorably to TNF blockade are still poorly characterized. The goal of this study was to identify biological features that explain this differential response using a multilevel transcriptome analysis of the synov...

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Bibliographische Detailangaben
Veröffentlicht in:Arthritis Res Ther
Hauptverfasser: Julià, Antonio, Ávila, Gabriela, Celis, Raquel, Sanmartí, Raimon, Ramírez, Julio, Marsal, Sara, Cañete, Juan D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7446220/
https://ncbi.nlm.nih.gov/pubmed/32843099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-020-02287-9
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