Riboswitch identification using Ligase-Assisted Selection for the Enrichment of Responsive Ribozymes (LigASERR)

In vitro selection of ligand-responsive ribozymes can identify rare, functional sequences from large libraries. While powerful, key caveats of this approach include lengthy and demanding experimental workflows; unpredictable experimental outcomes and unknown functionality of enriched sequences in vi...

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Bibliografiske detaljer
Udgivet i:Synth Biol (Oxf)
Main Authors: Haines, Matthew C, Storch, Marko, Oyarzún, Diego A, Stan, Guy-Bart, Baldwin, Geoff S
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7445825/
https://ncbi.nlm.nih.gov/pubmed/32995542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/synbio/ysz019
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