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Exploiting the sequence diversity of TALE-like repeats to vary the strength of dTALE-promoter interactions
Designer transcription activator-like effectors (dTALEs) are programmable transcription factors used to regulate user-defined promoters. The TALE DNA-binding domain is a tandem series of amino acid repeats that each bind one DNA base. Each repeat is 33–35 amino acids long. A residue in the center of...
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| Veröffentlicht in: | Synth Biol (Oxf) |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7445789/ https://ncbi.nlm.nih.gov/pubmed/32995505 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/synbio/ysx004 |
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