Caricamento...
Asymmetric Synthesis of a 5,6,7,8-Tetrahydro-1,6-naphthyridine Scaffold Leading to Potent Retinoid-Related Orphan Receptor γt Inverse Agonist TAK-828F
[Image: see text] An asymmetric synthesis of the tetrahydronaphthyridine scaffold of TAK-828F as a RORγt inverse agonist has been developed. The synthesis features a newly discovered atom-economical protocol for Heck-type vinylation of chloropyridine using ethylene gas, an unprecedented formation of...
Salvato in:
| Pubblicato in: | J Org Chem |
|---|---|
| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Chemical
Society
2020
|
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7445745/ https://ncbi.nlm.nih.gov/pubmed/32701287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.0c01311 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|