Tissue sodium excess is not hypertonic and reflects extracellular volume expansion

Our understanding of Na(+) homeostasis has recently been reshaped by the notion of skin as a depot for Na(+) accumulation in multiple cardiovascular diseases and risk factors. The proposed water-independent nature of tissue Na(+) could induce local pathogenic changes, but lacks firm demonstration. H...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Rossitto, Giacomo, Mary, Sheon, Chen, Jun Yu, Boder, Philipp, Chew, Khai Syuen, Neves, Karla B., Alves, Rheure L., Montezano, Augusto C., Welsh, Paul, Petrie, Mark C., Graham, Delyth, Touyz, Rhian M., Delles, Christian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7445299/
https://ncbi.nlm.nih.gov/pubmed/32839436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17820-2
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