A biphasic nanohydroxyapatite/calcium sulphate carrier containing Rifampicin and Isoniazid for local delivery gives sustained and effective antibiotic release and prevents biofilm formation

Long term multiple systemic antibiotics form the cornerstone in the treatment of bone and joint tuberculosis, often combined with local surgical eradication. Implanted carriers for local drug delivery have recently been introduced to overcome some of the limitations associated with conventional trea...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Qayoom, Irfan, Verma, Rahul, Murugan, Prem Anand, Raina, Deepak Bushan, Teotia, Arun Kumar, Matheshwaran, Saravanan, Nair, Nisanth N., Tägil, Magnus, Lidgren, Lars, Kumar, Ashok
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7445265/
https://ncbi.nlm.nih.gov/pubmed/32839480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-70726-3
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