Whole-genome sequencing and gene network modules predict gemcitabine/carboplatin-induced myelosuppression in non-small cell lung cancer patients

Gemcitabine/carboplatin chemotherapy commonly induces myelosuppression, including neutropenia, leukopenia, and thrombocytopenia. Predicting patients at risk of these adverse drug reactions (ADRs) and adjusting treatments accordingly is a long-term goal of personalized medicine. This study used whole...

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Veröffentlicht in:NPJ Syst Biol Appl
Hauptverfasser: Björn, Niclas, Badam, Tejaswi Venkata Satya, Spalinskas, Rapolas, Brandén, Eva, Koyi, Hirsh, Lewensohn, Rolf, De Petris, Luigi, Lubovac-Pilav, Zelmina, Sahlén, Pelin, Lundeberg, Joakim, Gustafsson, Mika, Gréen, Henrik
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7445166/
https://ncbi.nlm.nih.gov/pubmed/32839457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41540-020-00146-6
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