Immune dysregulation and multisystem inflammatory syndrome in children (MIS-C) in individuals with haploinsufficiency of SOCS1

BACKGROUND: We studied 2 unrelated patients with immune thrombocytopenia and autoimmune hemolytic anemia in the setting of acute infections. One patient developed multisystem inflammatory syndrome in children in the setting of a severe acute respiratory syndrome coronavirus 2 infection. OBJECTIVES:...

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Vydáno v:J Allergy Clin Immunol
Hlavní autoři: Lee, Pui Y., Platt, Craig D., Weeks, Sabrina, Grace, Rachael F., Maher, George, Gauthier, Kasey, Devana, Sridevi, Vitali, Sally, Randolph, Adrienne G., McDonald, Douglas R., Geha, Raif S., Chou, Janet
Médium: Artigo
Jazyk:Inglês
Vydáno: American Academy of Allergy, Asthma & Immunology 2020
Témata:
Brief Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7445138/
https://ncbi.nlm.nih.gov/pubmed/32853638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2020.07.033
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