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Upregulation of Superoxide Dismutase 2 by Astrocytes in the SIV/Macaque Model of HIV-Associated Neurologic Disease

HIV-associated neurocognitive disorders (HAND) remain prevalent despite implementation of antiretroviral therapy (ART). Development of HAND is linked to mitochondrial dysfunction and oxidative stress in the brain; therefore, upregulation of antioxidant defenses is critical to curtail neuronal damage...

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Veröffentlicht in:J Neuropathol Exp Neurol
Hauptverfasser: Sullivan, Michelle N, Brill, Samuel A, Mangus, Lisa M, Jeong, Yea Ji, Solis, Clarisse V, Knight, Audrey C, Colantuoni, Carlo, Keceli, Gizem, Paolocci, Nazareno, Queen, Suzanne E, Mankowski, Joseph L
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7445038/
https://ncbi.nlm.nih.gov/pubmed/32783052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnen/nlaa084
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